Treatment of Hepatitis C

Section Eight

Treatment of Hepatitis C

HCV inhibitors (also called Direct Acting Antivirals —DAA’s) are approved by the U.S. Food and Drug Administration (FDA) to treat hepatitis C.  The DAA’s are given with and without ribavirin to treat hepatitis C in genotypes 1, 2, 3, 4, 5 and 6.  The cure rates are up to 90 to 100%.  This is basic information.  There is more detailed information in our treatment section of the website.   The current medications used to treat chronic hepatitis C include:

  • Genotype 1:
    • Daklinza – one pill; taken with sofosbuvir.  Taken with and without ribavirin.  Two pills taken once-a-day.  Treatment duration is 12 weeks.
    • Harvoni – one pill; taken once-a-day. Taken with and without ribavirin.  Treatment duration is 8, 12 or 24 weeks.
    • Viekira Pak – several pills taken with and without ribavirin. Viekira Pak is taken twice daily. Ribavirin is taken twice daily. Treatment duration is 12 or 24 weeks.
    • Zepatier – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 or 16 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.
  • Genotype 2:
    • Sovaldi– one pill taken once-a-day taken with ribavirin. Treatment duration is 12 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.
  • Genotype 3:
    • Sovaldi one pill taken one-a-day.  Taken with ribavirin. Treatment duration is 24 weeks.
    • Daklinza is taken in combination with sofosbuvir.  Two pills taken once-a-day.  Treatment duration is 12 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.
  • Genotype 4:
    • Harvoni – one pill taken once-a-day.  Treatment duration is 12 weeks.
    • Technivie – one pill taken once-a-day.  Taken with and without ribavirin.  The treatment duration is 12 weeks.
    • Zepatier – pill taken once-a-day.  Taken with and without ribavirin.  The treatment duration is 12 or 16 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.
  •  Genotype 5:
    • Harvoni – one pill taken once-a-day.  Treatment duration is 12 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.
  • Genotype 6:
    • Harvoni – one pill taken once-a-day.  Treatment duration is 12 weeks.
    • Epclusa – one pill, taken once-a-day with and without ribavirin.  Treatment duration is 12 weeks.

warning Note: It is important to notify your medical provider if you are taking any prescription drugs, over-the-counter medications or herbal remedies. These drugs could affect how the HCV medications work.   Ribavirin Warning: Ribavirin has been shown to cause birth defects and miscarriages. Women of childbearing age, their male partners, and female partners of male patients taking ribavirin must use at least two forms of effective contraception during treatment and during the six-month post-treatment follow-up period. A woman should have a pregnancy test at certain time points during therapy.

Self-help Tip:

  • Your doctor or nurse will give you instructions on how to take the medications
  • If you miss a dose of medicine your medical provider will give you instructions on when to take the next dose
  • Always check in with your medical provider if you have any questions about treatment

 

GET TESTED.  GET TREATED.  GET CURED.

Next: Treatment Considerations

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